Michaela Müller-Trutwin

Jul 13, 2022

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Michaela Müller-Trutwin

Institut Pasteur

HIV, Inflammation and Persistence

mmuller@pasteur.fr

Website: https://research.pasteur.fr/en/team/hiv-inflammation-persistence/
ORCID: 0000-0002-3854-2396
Twitter: @MikiTrutwin

 

Top 5 publications

  1. Huot N, Jacquelin B, Garcia-Tellez T, Rascle P, Ploquin M, Madec Y, Reeves RK, Derreudre-Bosquet N & Müller-Trutwin M.  NK cells migrate into and control SIV replication in lymph node follicles in African green monkeys. Nat Med. 2017 Nov;23(11):1277-1286.
  2. Angin M, S Volant, Passaes C, C Lecuroux, V Monceaux, MA Dillies, JC Valle Casuso, Pancino P, Vaslin B, Le Grand R, Weiss L, Goujard C, Meyer L, F Boufassa, M Muller-Trutwin, O Lambotte, A Sáez-Cirión. Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection. Nature Metabolism. Volume 1, pages704–716 (2019).
  3. Huot N, Rascle P, Petitdemange C, Contreras V, Stürzel CM, Baquero E, Harper JL, Passaes C, Legendre R, Varet H, Madec, Sauermann, Stahl-Hennig, Nattermann, Saez-Cirion, Le Grand R, Reeves RK, Paiardini M, Kirchhoff F, Jacquelin B & Müller-Trutwin M. SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity. Nat Comm 2021 Feb 24;12(1):1282. doi: 10.1038/s41467-021-21402-1.
  4. Harper J*, Huot N*, Micci L, Tharp G, King C, Rascle P, Shenvi N, Wang H, Galardi C, Upadhyay AA, Villinger F, Lifson J, Silvestri G, Easley K, Jacquelin B, Bosinger S, Müller-Trutwin M*, Paiardini M*. IL-21 and IFN-a therapy rescues the terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques. Nat Comm. 2021 May 17;12(1):2866. * co-first and co-last authors
  5. Federico Perdomo-Celis, Caroline Passaes, Valérie Monceaux, Stevenn Volant, Faroudy Boufassa, Pierre de Truchis, Morgane Marcou, Katia Bourdic, Laurence Weiss, Corinne Jung, Christine Bourgeois, Cecile Goujard, Laurence Meyer, Michaela Müller-Trutwin, Olivier Lambotte and Asier Sáez-Cirión. Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control. J Clin Invest. 2022 Apr 5:e157549. doi: 10.1172/JCI157549.

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