Website: https://research.pasteur.fr/en/team/hiv-inflammation-persistence/
ORCID: 0000-0002-3854-2396
Twitter: @MikiTrutwin
Top 5 publications
- Huot N, Jacquelin B, Garcia-Tellez T, Rascle P, Ploquin M, Madec Y, Reeves RK, Derreudre-Bosquet N & Müller-Trutwin M. NK cells migrate into and control SIV replication in lymph node follicles in African green monkeys. Nat Med. 2017 Nov;23(11):1277-1286.
- Angin M, S Volant, Passaes C, C Lecuroux, V Monceaux, MA Dillies, JC Valle Casuso, Pancino P, Vaslin B, Le Grand R, Weiss L, Goujard C, Meyer L, F Boufassa, M Muller-Trutwin, O Lambotte, A Sáez-Cirión. Metabolic plasticity of HIV-specific CD8+ T cells is associated with enhanced antiviral potential and natural control of HIV-1 infection. Nature Metabolism. Volume 1, pages704–716 (2019).
- Huot N, Rascle P, Petitdemange C, Contreras V, Stürzel CM, Baquero E, Harper JL, Passaes C, Legendre R, Varet H, Madec, Sauermann, Stahl-Hennig, Nattermann, Saez-Cirion, Le Grand R, Reeves RK, Paiardini M, Kirchhoff F, Jacquelin B & Müller-Trutwin M. SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity. Nat Comm 2021 Feb 24;12(1):1282. doi: 10.1038/s41467-021-21402-1.
- Harper J*, Huot N*, Micci L, Tharp G, King C, Rascle P, Shenvi N, Wang H, Galardi C, Upadhyay AA, Villinger F, Lifson J, Silvestri G, Easley K, Jacquelin B, Bosinger S, Müller-Trutwin M*, Paiardini M*. IL-21 and IFN-a therapy rescues the terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques. Nat Comm. 2021 May 17;12(1):2866. * co-first and co-last authors
- Federico Perdomo-Celis, Caroline Passaes, Valérie Monceaux, Stevenn Volant, Faroudy Boufassa, Pierre de Truchis, Morgane Marcou, Katia Bourdic, Laurence Weiss, Corinne Jung, Christine Bourgeois, Cecile Goujard, Laurence Meyer, Michaela Müller-Trutwin, Olivier Lambotte and Asier Sáez-Cirión. Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control. J Clin Invest. 2022 Apr 5:e157549. doi: 10.1172/JCI157549.
Dernières publications sur HAL :
- [pasteur-04129134] NK cell spatial dynamics and IgA responses in gut-associated lymphoid tissues during SIV infectionsby ano.nymous@ccsd.cnrs.fr.invalid (Philippe Rascle) on 15 June 2023 at 9h48
Abstract HIV infection induces tissue damage including lymph node (LN) fibrosis and intestinal epithelial barrier disruption leading to bacterial […]
- [hal-03599642] Optimal Maturation of the SIV-Specific CD8+ T Cell Response after Primary Infection Is Associated with Natural...by ano.nymous@ccsd.cnrs.fr.invalid (Caroline Passaes) on 23 September 2022 at 11h24
Highly efficient CD8+ T cells are associated with natural HIV control, but it has remained unclear how these cells are generated and maintained. We […]
- [hal-03699427] CXCR3 Expression Pattern on CD4+ T Cells and IP-10 Levels with Regard to the HIV-1 Reservoir in the Gut-Associated...by ano.nymous@ccsd.cnrs.fr.invalid (Max Augustin) on 20 June 2022 at 16h33
Background: The gut-associated lymphatic tissue (GALT) represents the largest lymphoid organ, and is considered to be the largest HIV reservoir. The […]
- [pasteur-03682118] NK-B cell cross talk induces CXCR5 expression on natural killer cellsby ano.nymous@ccsd.cnrs.fr.invalid (Philippe Rascle) on 30 May 2022 at 17h26
B cell follicles (BCFs) in lymph nodes (LNs) are generally exempt of CD8+ T and NK cells. African green monkeys (AGMs), a natural host of simian […]